'
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.4
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Proprietary Probiotic BlendLacticaseibacillus rhamnosus R0011Lactobacillus helvetius R0052Pediococcus acidilactici R1001Lacticaseibacillus casei R0215Bifidobacterium longum BB536Lactiplantibacillus plantarum R1012Bifidobacterium breve R0070Lactococcus lactis subsp. lactis R1058
131 mg (10 Billion CFU)

Top Medical Research Studies

9
L. plantarum reduces heart disease risk
Anti-atherosclerotic effects of Lactobacillus plantarum ATCC 14917 in ApoE mice through modulation of proinflammatory cytokines and oxidative stress.
Promising but requires further study
We set out to explore the effects of Lactobacillus plantarum ATCC 14917 on heart disease in ApoE-deficient mice. Over 12 weeks, these mice were given the probiotic, and we analyzed their heart health and inflammation levels.

The results were intriguing; while L. plantarum didn’t impact body weight or overall fat levels, it did significantly reduce atherosclerotic lesions. Additionally, markers of inflammation and oxidative stress improved, suggesting this probiotic might help slow heart disease progression.
Read More
9
Lactobacillus plantarum reduces cholesterol
An in vivo assessment of the cholesterol-lowering efficacy of Lactobacillus plantarum ECGC 13110402 in normal to mildly hypercholesterolaemic adults.
Highly relevant to cardiovascular health
We investigated how Lactobacillus plantarum ECGC 13110402 affects cholesterol levels in a group of 49 adults with normal to mildly high cholesterol. This double-blind, placebo-controlled study showed promising results. Specifically, we observed a notable decrease in LDL cholesterol and triglycerides after 12 weeks, alongside a rise in HDL cholesterol.

Additionally, systolic blood pressure reduced significantly in participants over 60 during the study. Importantly, the probiotic was well-tolerated with no gastrointestinal side effects. Overall, this strain shows potential as a natural option to help reduce heart disease risk.
Read More
9
Probiotic improves vascular function
Lactobacillus plantarum 299v Supplementation Improves Vascular Endothelial Function and Reduces Inflammatory Biomarkers in Men With Stable Coronary Artery Disease.
Relevant findings on heart health
We looked into whether the probiotic Lactobacillus plantarum 299v (Lp299v) can improve heart health by enhancing vascular function and reducing inflammation in men with stable coronary artery disease (CAD).

Over six weeks, twenty men consumed Lp299v, leading to improved blood vessel function and reduced levels of certain inflammatory markers.

Notably, there were no significant changes in traditional risk factors like cholesterol levels. Our findings suggest that Lp299v holds promise for heart health, particularly through its effects on gut-derived metabolites.
Read More

Most Useful Reviews

0
No improvement noted
I initially thought this supplement was effective but soon developed a skin condition resembling atopy. After stopping the supplement and trying various remedies without success, I experienced intense itching on my neck, abdomen, and eyelids. Ceasing this supplement led to immediate improvement. Ultimately, it was not suitable for me. I am now seeing positive effects with a different lactic acid bacterium and no longer have any atopy.
Read More
2.5
Sharp stomach pain
I had been searching for a good probiotic for some time, especially due to my chronic diseases and frequent antibiotics. However, I experienced severe stomach pain shortly after starting this product. Despite my efforts to persist, it wasn't worth it. I ended up giving it to a friend who suffers from constipation, and it proved beneficial for them.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
9
Lactobacillus plantarum improves lipid profiles
Probiotic Lactobacillus plantarum may reduce cardiovascular risk: An experimental study.
Highly relevant cardiovascular findings
We investigated whether adding Lactobacillus plantarum to standard simvastatin treatment could reduce cardiovascular risk in dyslipidemic patients. In a study with 77 participants aged 40-74, we found that the combination therapy significantly lowered total cholesterol and LDL levels after 8 and 12 weeks.

The results showed not only a noteworthy decline in lipid levels but also in cardiovascular risk scores for those receiving the probiotic. This suggests that Lactobacillus plantarum may enhance heart health when used alongside traditional medications.
Read More
9
L. plantarum reduces heart disease risk
Anti-atherosclerotic effects of Lactobacillus plantarum ATCC 14917 in ApoE mice through modulation of proinflammatory cytokines and oxidative stress.
Promising but requires further study
We set out to explore the effects of Lactobacillus plantarum ATCC 14917 on heart disease in ApoE-deficient mice. Over 12 weeks, these mice were given the probiotic, and we analyzed their heart health and inflammation levels.

The results were intriguing; while L. plantarum didn’t impact body weight or overall fat levels, it did significantly reduce atherosclerotic lesions. Additionally, markers of inflammation and oxidative stress improved, suggesting this probiotic might help slow heart disease progression.
Read More
9
Probiotic improves vascular function
Lactobacillus plantarum 299v Supplementation Improves Vascular Endothelial Function and Reduces Inflammatory Biomarkers in Men With Stable Coronary Artery Disease.
Relevant findings on heart health
We looked into whether the probiotic Lactobacillus plantarum 299v (Lp299v) can improve heart health by enhancing vascular function and reducing inflammation in men with stable coronary artery disease (CAD).

Over six weeks, twenty men consumed Lp299v, leading to improved blood vessel function and reduced levels of certain inflammatory markers.

Notably, there were no significant changes in traditional risk factors like cholesterol levels. Our findings suggest that Lp299v holds promise for heart health, particularly through its effects on gut-derived metabolites.
Read More
9
Lactobacillus plantarum reduces cholesterol
An in vivo assessment of the cholesterol-lowering efficacy of Lactobacillus plantarum ECGC 13110402 in normal to mildly hypercholesterolaemic adults.
Highly relevant to cardiovascular health
We investigated how Lactobacillus plantarum ECGC 13110402 affects cholesterol levels in a group of 49 adults with normal to mildly high cholesterol. This double-blind, placebo-controlled study showed promising results. Specifically, we observed a notable decrease in LDL cholesterol and triglycerides after 12 weeks, alongside a rise in HDL cholesterol.

Additionally, systolic blood pressure reduced significantly in participants over 60 during the study. Importantly, the probiotic was well-tolerated with no gastrointestinal side effects. Overall, this strain shows potential as a natural option to help reduce heart disease risk.
Read More
9
Lactobacillus plantarum lowers blood pressure
Effective treatment of hypertension by recombinant Lactobacillus plantarum expressing angiotensin converting enzyme inhibitory peptide.
Highly relevant hypertension treatment
We investigated whether Lactobacillus plantarum could help combat high blood pressure, a major risk factor for heart disease. By using a special strain, we were able to express angiotensin-converting enzyme inhibitory peptides and test their effects on spontaneously hypertensive rats.

Our findings were promising; after treatment, systolic blood pressure significantly decreased, and beneficial changes in important biological markers were observed, without major side effects. This suggests that Lactobacillus plantarum could be a safe and effective approach to managing hypertension and supporting heart health.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 2 Reviews
7.4
2.5
Sharp stomach pain
I had been searching for a good probiotic for some time, especially due to my chronic diseases and frequent antibiotics. However, I experienced severe stomach pain shortly after starting this product. Despite my efforts to persist, it wasn't worth it. I ended up giving it to a friend who suffers from constipation, and it proved beneficial for them.
Read More
0
No improvement noted
I initially thought this supplement was effective but soon developed a skin condition resembling atopy. After stopping the supplement and trying various remedies without success, I experienced intense itching on my neck, abdomen, and eyelids. Ceasing this supplement led to immediate improvement. Ultimately, it was not suitable for me. I am now seeing positive effects with a different lactic acid bacterium and no longer have any atopy.
Read More
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